Pentatricopeptide repeats
نویسندگان
چکیده
منابع مشابه
Human pentatricopeptide proteins
Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Originally identified in Arabidopsis thaliana, family members are found in protists, fungi, and metazoan but are by far most abundant in plant organelles. Seven examples have been identified in human mitochondria and roles have been tentatively ascribed to ...
متن کاملPentatricopeptide repeat proteins
Mitochondria and chloroplasts host genomes inherited from their bacterial ancestors. Their biogenesis thus requires fully functional gene expression machineries. RNA metabolism in organ-elles is particular and has attracted considerable attention since it combines prokaryotic features with unique traits that evolved in their eukaryotic host cell. For a long time, most of the molecular factors g...
متن کاملChloroplast RNA editing by pentatricopeptide repeat proteins.
Pentatricopeptide repeat (PPR) proteins function in multiple processes in mRNA maturation in plastids and mitochondria (reviewed in Schmitz-Linneweber and Small, 2008). RNA maturation in chloroplasts is complex, and PPR proteins act in cisand trans-splicing, translation, RNA cleavage, RNA stabilization, and RNA editing. This large protein family, with 450 members in Arabidopsis, is characterize...
متن کاملFormation of the Arabidopsis pentatricopeptide repeat family.
In Arabidopsis (Arabidopsis thaliana) the 466 pentatricopeptide repeat (PPR) proteins are putative RNA-binding proteins with essential roles in organelles. Roughly half of the PPR proteins form the plant combinatorial and modular protein (PCMP) subfamily, which is land-plant specific. PCMPs exhibit a large and variable tandem repeat of a standard pattern of three PPR variant motifs. The associa...
متن کاملChloroplast RNA-binding and pentatricopeptide repeat proteins.
Chloroplast gene expression is mainly regulated at the post-transcriptional level by numerous nuclear-encoded RNA-binding protein factors. In the present study, we focus on two RNA-binding proteins: cpRNP (chloroplast ribonucleoprotein) and PPR (pentatricopeptide repeat) protein. These are suggested to be major contributors to chloroplast RNA metabolism. Tobacco cpRNPs are composed of five diff...
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ژورنال
عنوان ژورنال: RNA Biology
سال: 2013
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.24769